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LGD 4033 was developed with the goal of preventing muscle loss in the elderly and in those who suffer from muscle dystrophy, and to prevent the loss of strength and mass associated with muscle degeneration and/or atrophy. The study was designed to compare 3 different dose regimens. The first, as discussed above, consisted of a single dose of 4033. This was taken twice daily in a total of 9,500 mg. The next two regimens included a single dose of 4033 in 2 doses (30 and 50 mg) divided into 6 daily doses. Each dose was taken approximately 30 minutes before an 8-hour period of light exercise. Both regimens were supplemented with the creatine monohydrate monohydrate blend. The latter was used to prevent muscle breakdown, as the former was not effective. Each dose was taken once in each day until 4 days have been observed. The study was also designed to compare the effects of the 3 different regimens on muscle strength, blood levels of creatine and/or its breakdown products. All subjects received a post-exercise test with an objective of measuring anaerobic capacity. The test included the same protocol as the study on aerobic capacity as well as the same testing protocols used to measure muscle strength, blood levels of creatine and creatine breakdown products. Results Subjects and characteristics The study group consisting of the 4 men and 3 women ranged in age from 40 to 67 years with mean ± SD: 37 ± 12 years, with a BMI of 24 ± 6 kg/m2. The mean age was higher than that of the non-study group (33 ± 13 years versus 30 ± 8 years). Two subjects were overweight. There were no other significant characteristics of the study participants. All of the subjects were free of other conditions, and all were not receiving supplemental oxygen therapy before the study. There were no changes in body weight, bone mineral density or blood testosterone levels across the 4 study days. Study design and testing Tissues were processed to determine tissue distribution, mass, and the extent to which creatine and its metabolism were determined. The test used in the present study was that of an anabolic exercise endurance test using an incremental test protocol (20–30 minutes of intense running/jogging). Subjects ran 20 km (10 mi) at a pace of 9-9.9 km/h (6.2–6.6mph), completing the test in 5 minutes. The test was a timed one-arm vertical jump and leg press. The subjects were wearing an oxygen concentrator or an anabolic oxygen monitor at Similar articles:
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